Archives
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br In vivo safety and tumor penetration
2022-09-17
3.6. In vivo safety and tumor penetration To evaluate the safety and the tumor penetration in vivo, [email protected]&PTX and [email protected] were investigated by intravenous administration into HepG2 subcutaneous tumor-bearing nude mice. DOX + PTX, free DOX, and saline were used as controls. The mice were s
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br According to the results it can be concluded that
2022-09-17
According to the results, it gamma-Glu-Cys can be concluded that the CAD is suitable to help the doctor for making diagnosis decision. Com-pared with previous study (Zulfanahri et al., 2017; Nugroho et al., 2017a,b), the proposed method also obtains high accuracy. However, this work still has som
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br Methods We identified children
2022-09-17
Methods: We identified children age 18 years with blunt injury AIS 2 treated from 2010 to 2013 at 130 U.S trauma centers participating in the Trauma Quality Improvement Program. CT rates were compared across center types using Chi-square analysis. Stratified analyses in children with varying injur
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br Surgical complications were also similar for both
2022-09-17
Surgical complications were also similar for both groups with no difference reaching clinical significance (Table 3). Importantly, 90-day osteomyelitis and infection rates were similar for both groups. When assessing Medicare expenditure, we found no statistically significant difference in the
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br Methods mRNA expression of COMP was compared
2022-09-16
Methods: mRNA K 252a of COMP was compared to that of EMT markers using the UCSC Cancer Genomics Browser. Survival analysis was performed using the UCSC Xena Browser for cancer genomics. Results: Expression analysis revealed coexpression of COMP with the EMT markers CDH2, FN1, VIM, TWIST1, TWIS
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br There are several limitations to the
2022-09-15
There are several limitations to the current study. The sample size is modest due to the requirement that patient must have post-DRE urine supernatant available since we did not have sufficient quantities of urinary cell sediment available for miRNA analysis. Although the 3-marker panel requires a
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br efficient in vivo in a
2022-09-15
efficient in vivo, in a breast cancer bone metastasis model, and 2) if such combinatorial delivery is more beneficial than either therapeutic alone. After verifying the presence of the tumour within the tibia of mice (typ-ically 2 weeks post cancer induction), we injected 1 × 105 MSC engineered
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br nm emission filter Fold
2022-09-15
505 nm emission filter. Fold-increase of caspase activity was deter-mined by comparison of treated samples to untreated samples. For the Caspase-Glo assay, cells were plated in 96-well dishes at 4500 cells/well and allowed to incubate overnight. After transfection (see below) cells were treated
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br Statistical analysis br Statistical analyses were
2022-09-14
5. Statistical analysis Statistical analyses were performed using GraphPad Prism 5 soft-ware. Results are presented as mean values ± standard deviations (S.D.) and/or standard errors of the means (S.E.M.) for quantitative data. Statistical significance was determined using ANOVA with the Tukey'
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br cancer therapy The hypothesis has been
2022-09-14
cancer therapy. The hypothesis has been proved by previous studies, which showed that a CD44-targeting HA-decorated bio-compatible oligomer containing Vitamin E and styrene maleic anhydride exhibits excellent triple-negative breast cancer tumor accumulation and selectively kills triple-negative
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br Distant failure after isolated pelvic failure
2022-09-08
3.2. Distant failure after isolated pelvic failure The median time to distant failure after isolated pelvic recurrence was 20 months (95% CI 3–37) (Fig. 1A). Of the 23 patients found to have distant failure, 22 (96%) failed within 2 years of the initial isolated pelvic failure. Median time to d
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Deferoxamine br Curran Jr WJ Paulus
2022-09-08
[2] Curran Jr WJ, Paulus R, Langer CJ, Komaki R, Lee JS, Hauser S, et al. Sequential vs. concurrent chemoradiation for stage III non-small cell lung cancer: randomized phase III trial RTOG 9410. J Natl Cancer Inst 2011;103:1452–60. [3] St James S, Grassberger C, Lu HM. Considerations when treatin
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br Corresponding author at Department of Radiation Oncology Unit
2022-09-08
⇑ Corresponding author at: Department of Radiation Oncology, Unit 1422, The University of Texas MD Anderson Cancer Center, 1220 Holcombe Blvd, Houston, TX 77030-4004, USA. E-mail address: [email protected] (Q.-N. Nguyen). volume layer by layer [3,4]. IMPT allows tight control and confo
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br Knockdown of CLDN gene by siRNA
2022-09-08
Knockdown of CLDN7 gene by siRNA The A 61603 were seeded in 6 or 10-cm Petri dishes (Corning Inc., Corning, NY, USA or TPP Techno Plastic Products, Trasadingen, Switzerland). Following overnight incubation, siRNA specific for CLDN7 or negative control siRNA (Sigma-Aldrich, St. Louis, MO, USA)
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Dynasore br Fig Example of an Inception module br Fig The
2022-09-08
Fig. 2. Example of an Inception module. Fig. 3. The whole training process of our proposed algorithm. problem in medical image analysis research. Moreover, combining the Inception architecture with residual connections can lead to dramatically improved training speeds, and can significantly