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br Department of Orthopedics Guangzhou First People s Hospit
2020-08-12
10 Department of Orthopedics, Guangzhou First People's Hospital, the Second Affiliated Hospital of South China University of Technology, Guangzhou, Guangdong 510180, People's Republic of China, E-mail: [email protected] 11 Department of Orthopedics, Guangzhou First People's Hospital, Guangzhou Me
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br Fig Apatinib enhanced the pro
2020-08-12
Fig. 3. Apatinib enhanced the pro-apoptotic effect of cisplatin on MDA-MB-231 cells. MDA-MB-231 6-Hydroxydopamine were treated with cisplatin (5 μM) or/and apatinib (10 μM) for 72 h. (A) Apoptotic cells were measured with Annexin V and PI double staining. (B) The apoptosis cell rates were calculat
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br Competing interests br The authors
2020-08-12
Competing interests The authors declare that no competing interests exist. References [5] R.W. Rickards, J.M. Rothschild, A.C. Willis, N.M. de Chazal, J. Kirk, K. Kirk, et al., Calothrixins A and B, novel pentacyclic metabolites from Calothrix 1977535-33-3 with potent activity against ma
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br Inhibition of the AR in prostate cancer may
2020-08-12
Inhibition of the AR in prostate cancer may contribute the most to malignant transformation and tumors progressing to CRPC [56–58]. We demonstrated a role of the ZBTB46 protein for the NE transformation of prostate cancer and identified ZBTB46 as a novel effector of aberrant AR signaling. A key mec
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br Data management was performed
2020-08-12
Data management was performed using Microsoft Excel version 2016 (Seattle, Washington). Statistical analysis was performed using STATA version 14.0 (StataCorp LP, Col-lege Station, TX). Pearson chi-square and Fisher’s exact test were used to comparing proportions of categorical variables. Wilcoxon
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br In this study the results of tests and were
2020-08-12
In this study, the results of tests 1 and 3 were compared; then, the significant improvement in the diagnostic accu-racy of M-NBI after the e-learning training was confirmed. In this secondary analysis, analysis of learning effects was performed by dividing the lesion into fine features. In addi-t
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br Competing financial interests declaration br The author h
2020-08-12
Competing financial interests declaration The author has previously done consulting for EPRI, not related to this work. Financial support No external funding was obtained for this study. Appendix A. Supporting information References Ahlbom, A., Feychting, M., Green, A., Kheifets,
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br In this study Y was used to
2020-08-12
In this study, Y27632 was used to enhance phagocytosis, which was previously known as the Rho kinase inhibitor that blocks RhoA/ROCK signaling (Nam et al., 2018). In agreement with the previous report, the result of the phagocytosis assay using CellTracker dye showed that the percentage (%) of the
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br Murtola T J Syv l H
2020-08-12
[24] Murtola, T.J., Syvälä, H., Tolonen, T., Helminen, M., Riikonen, J., Koskimäki, J., et al., 2018. Atorvastatin versus placebo for prostate cancer before radical prostatectomy e a randomized, double-blind, placebo-controlled clinical trial. European Urology 74(6):697e701. [28] Hao, J., Ci, X
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Fer 1 br Fig Amplifications of FGFR
2020-08-12
37 Fig. 1 Amplifications of FGFR1 (Cases 30, 8, and 9) (A-H), ZNF703 (Case 18) (I), and MYC (Cases 19 and 53) (J-L) (orange, gene-specific signals; green, signals for the centromeric regions on which the specific genes are located). In Panel D, paired signals of FGFR1 and centromere 8 (small arro
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br Inhibition of cytokines TNF a and interleukins
2020-08-07
2.5.3. Inhibition of cytokines (TNF-a and interleukins) TNF- a (Tumor necrosis factor alpha) which is produced in im-mune and tumor BQ-788 sodium salt plays a central role in inflammation, apoptosis, and cancer progression. Cell surface TNF-a can induce lysis in tumor cells or surrounding cell
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Ethylmalonyl Coenzyme A br As shown in Fig all compounds tes
2020-08-07
As shown in Fig. 4, all compounds tested significantly increased calcium levels. Taking into account that the ER acts as the major calcium store in Ethylmalonyl Coenzyme A (Pereira et al., 2018, 2015a), we hypothesized that this organelle could be involved in the toxicity elicited by benzoquin
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br MODEL br Asian Surgical Association and Taiwan
2020-08-07
+ MODEL ª 2019 Asian Surgical Association and Taiwan Robotic Surgery Association. Publishing services by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http:// creativecommons.org/licenses/by-nc-nd/4.0/). 1. Introduction Colorectal cancer (CRC) is the most com
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Paclitaxel (Taxol) br autophagy blockade Such a
2020-08-07
autophagy blockade. Such a hypothesis was previ-ously demonstrated in colon cancer Paclitaxel (Taxol) [21], although convincing evidence in the skeletal muscle is lacking. In this regard, previous data reported that either proteasome [4] or calpain [22] inhibition does not improve cancer-induce
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br Western blot analysis br The cells were
2020-08-06
2.9. Western blot analysis The cells were seeded at a density of 5 × 106 cells in a 100 mm dish, and then cultured for 24 h in DMEM. After culturing, the cells were treated with the indicated concentrations of AC and TRAIL for 24 h, followed by centrifugation. The resulting pellets were lyse